“Natural Site-Directed Mutagenesis” Might Exist in Eukaryotic Cells
نویسنده
چکیده
Site-directed mutagenesis refers to a man-made molecular biology method that is used to make genetic alterations in the DNA sequence of a gene of interest. But based on our recently published experimental findings, we propose that “natural site-directed mutagenesis” might exist in eukaryotic cells, which is triggered by harmful agents and co-directed by special transcription hotspots and mutation-contained intranuclear primers.
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تاریخ انتشار 2016